In 1946, University of Chicago researchers Anton Carlson and Frederick Hoelzel subjected rats to periodic food restriction and found, when they did, that those that went hungry every third day lived 15 to 20 percent longer than their cousins on a regular diet.
It’s not clear whether the pair applied what they’d learned to their own lives, but both lived relatively long lives for their time. Carlson died at the age of 81. Hoelzel made it to 74, despite having subjected himself over the years to experiments that included swallowing gravel, glass beads, and ball bearings to study how long it would take for such objects to pass through his system. And people say I’m crazy.